i-zik:

Hey guys and good morning! Want to start the day with a shoutout! @autobot.windblade herself is one of the first people I ever Rp’ed with on Instagram. She’s a great role player, and has a wonderful page dedicated to the character Windblade (no brainer there) check her out! I’ll be doing one shout out a day from now on. Magnus out! (Or maybe ShoutOut Sundays would be better…meh we’ll see xD) #windblade #ultramagnus #transformersg1 #transformers #autobots #cybertron

(Reblogged from i-zik)
(Reblogged from goddesslisann)

Watch Mojo’s Top 10 Video Games of the 6th Generation

(Reblogged from dailyactress)

modelmylove:

Candice, color, bikini, and feeling the sun love.

(Reblogged from modelmylove)

neurosciencenews:

Children with Autism Have Extra Synapses in Brain

Read the full article Children with Autism Have Extra Synapses in Brain at NeuroscienceNews.com.

Children and adolescents with autism have a surplus of synapses in the brain, and this excess is due to a slowdown in a normal brain “pruning” process during development, according to a study by neuroscientists at Columbia University Medical Center (CUMC). Because synapses are the points where neurons connect and communicate with each other, the excessive synapses may have profound effects on how the brain functions.

The research is in Neuron. (full access paywall)

Research: “Loss of mTOR-Dependent Macroautophagy Causes Autistic-like Synaptic Pruning Deficits” by Guomei Tang, Kathryn Gudsnuk, Sheng-Han Kuo, Marisa L. Cotrina, Gorazd Rosoklija, Alexander Sosunov, Mark S. Sonders, Ellen Kanter, Candace Castagna, Ai Yamamoto, Zhenyu Yue, Ottavio Arancio, Bradley S. Peterson, Frances Champagne, Andrew J. Dwork, James Goldman, and David Sulzer in Neuron. doi:10.1016/j.neuron.2014.07.040

Image: 1) A neuron from the brain of young person with autism. A new study finds that young people with autism have excess synapses. Credit Guomei Tang and Mark S. Sonders/CUMC.

2) Autistic brains do not undergo normal pruning during childhood and adolescence. The images show representative neurons from autistic (left) and control (right) brains; the spines on the neurons indicate the location of synapses. Credit Guomei Tang and Mark S. Sonders/CUMC.

3) A “self-eating” impairment in the neurons of autism patients is shown with the decrease of an autophagy marker (red color) compared to unaffected neurons. Credit Guomei Tang/CUMC.

(Reblogged from neurosciencenews)

Marvel’s Guardians of the Galaxy - Clip 5

Marvel’s Guardians of the Galaxy - Clip 4